The Human Brain in a Dish: The Promise of iPSC-Derived Neurons | Zendy

Ricardo E. Dolmetsch | Zendy; Daniel H. Geschwind | Zendy

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The Human Brain in a Dish: The Promise of iPSC-Derived Neurons

Author(s) -

Ricardo E. Dolmetsch,

Daniel H. Geschwind

Publication year - 2011

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2011.05.034

Subject(s) - induced pluripotent stem cell , biology , neuroscience , disease , mechanism (biology) , human induced pluripotent stem cells , bioinformatics , embryonic stem cell , medicine , gene , pathology , genetics , philosophy , epistemology

Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.

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