A Hormone Sends Instant Messages to the Genome
Author(s) -
Andreas Prokesch,
Mitchell A. Lazar
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.04.016
Subject(s) - transcriptome , biology , estrogen receptor , gene , computational biology , genetics , gene expression , breast cancer , cancer
Bridging a gap between transcriptomics and the study of cis-acting elements (cistromics), Hah et al. (2011) apply a next-generation sequencing technique to gain an unprecedented view of the changes in RNA synthesis that occur following estrogen receptor activation in human breast cancer cells.
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