Open AccessAn Exciting Calcium Sensor for Smell
Author(s) -
Natalia L. Konko,
Volker Haucke
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.03.047
Subject(s) - olfactory bulb , biology , granule cell , neuroscience , olfactory system , synaptotagmin 1 , sensory system , synapse , central nervous system , synaptic vesicle , biochemistry , dentate gyrus , vesicle , membrane
Formation of sensory maps within the olfactory bulb depends on insulin-like growth factor (IGF) signaling. Cao et al. (2011) now show that neuronal IGF secretion is regulated by neural activity through the calcium sensor synaptotagmin-10 and is required in the olfactory bulb for the sensation of smell.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom