Open AccessThe Ribosome and TORC2: Collaborators for Cell Growth
Author(s) -
Xiaoduo Xie,
KunLiang Guan
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.02.029
Subject(s) - biology , ribosome , regulator , cell growth , key (lock) , microbiology and biotechnology , computational biology , genetics , rna , gene , ecology
The target of rapamycin complex 2 (TORC2) is a key regulator of cell growth. Zinzalla et al. (2011) now provide evidence that TORC2 is activated by direct association with the ribosome, which may ensure that TORC2 activity is calibrated to match the cell's intrinsic growth capacity.
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