The Skeleton: The New Controller of Male Fertility? | Zendy

Lee B. Smith | Zendy; Philippa T. K. Saunders | Zendy

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The Skeleton: The New Controller of Male Fertility?

Author(s) -

Lee B. Smith,

Philippa T. K. Saunders

Publication year - 2011

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2011.02.028

Subject(s) - biology , skeleton (computer programming) , testosterone (patch) , fertility , male fertility , osteocalcin , endocrinology , hormone , medicine , anatomy , population , alkaline phosphatase , demography , sociology , biochemistry , enzyme

Sex steroids, including testosterone, regulate the development and function of the male skeleton. Oury et al. (2011) identify a surprising new connection between the skeleton and the testis, which has implications for male fertility. They show that testosterone production in the testis is directly influenced by the bone-derived hormone osteocalcin.

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