Open AccessIL-7 Knocks the Socs Off Chronic Viral Infection
Author(s) -
Ian A. Parish,
Susan M. Kaech
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.01.038
Subject(s) - immune system , biology , immunology , chronic infection , virology , t cell
Chronic viral infections represent a major burden to human health, and modulation of the immune system is emerging as a novel approach to fighting such infections. Pellegrini et al. (2011) demonstrate that treatment with the cytokine IL-7 may reinvigorate the immune response to persistent infection by targeting immunosuppressive Socs3 proteins.
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