Open AccessConsequences of mRNA Wardrobe Malfunctions
Author(s) -
Carol J. Wilusz,
Jeffrey Wilusz
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.11.041
Subject(s) - biology , genetics , messenger rna , computational biology , evolutionary biology , gene
As mRNAs are generated, they are clothed with proteins to form messenger ribonucleoprotein particles (mRNPs), which are then actively remodeled during various steps of gene expression. Franks et al. (2010) now show that mRNP remodeling is required even for the death of an mRNA.
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