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Up a Hydrophobic Creek with a Short Paddle
Author(s) -
Raymond E. Hulse,
Qufei Li,
Eduardo Perozo
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.08.005
Subject(s) - ion channel , membrane potential , voltage gated ion channel , transmembrane domain , ion , biology , biophysics , membrane , physics , nanotechnology , materials science , biochemistry , receptor , quantum mechanics
The mechanism by which voltage-dependent ion channels sense membrane potentials has been the most intensively studied and debated topic in modern ion channel research. In this issue, Xu et al. (2010) provide new insights into the minimal topological and physicochemical features required for voltage sensing.

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