Copy Coats: COPI Mimics Clathrin and COPII
Author(s) -
Frederick M. Hughson
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.06.031
Subject(s) - biology , copi , copii , clathrin , microbiology and biotechnology , golgi apparatus , genetics , secretory pathway , vesicle , endoplasmic reticulum , membrane
The assembly of COPI into a cage-like lattice sculpts membrane vesicles that transport cargo from the Golgi apparatus. Now, Lee and Goldberg (2010) present X-ray crystal structures of COPI suggesting that these coats combine selected features of two other archetypal coats, clathrin and COPII.
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