Open AccessATM Creates a Veil of Transcriptional Silence
Author(s) -
Michael S.Y. Huen,
Junjie Chen
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.05.035
Subject(s) - biology , dna damage , dna , transcription (linguistics) , microbiology and biotechnology , genetics , transcription factor , silence , dna repair , gene , linguistics , philosophy , aesthetics
The ATM kinase orchestrates diverse responses to DNA damage. By simultaneously monitoring transcription and DNA-damage responses in single cells, Shanbhag et al. (2010) now uncover a role of ATM in preventing transcription near DNA double-strand breaks.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom