Open AccessMicroRNAs: From Decay to Decoy
Author(s) -
Michaela Beitzinger,
Gunter Meister
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.02.020
Subject(s) - biology , decoy , microrna , computational biology , genetics , gene , receptor
MicroRNAs interact with Argonaute proteins to guide posttranscriptional gene silencing. Eiring et al. (2010) now show that miR-328 has a second function, acting as a decoy by binding to hnRNP E2 and lifting its translational repression of an mRNA involved in myeloid cell differentiation.
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