Open AccessLin28: A MicroRNA Regulator with a Macro Role
Author(s) -
Srinivas R. Viswanathan,
George Q. Daley
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.02.007
Subject(s) - lin28 , biology , microrna , regulator , rna interference , carcinogenesis , microbiology and biotechnology , genetics , computational biology , transcription factor , rna , gene , sox2
Lin28, a highly conserved RNA-binding protein, has emerged as a modulator of the processing of the let-7 microRNA. This role for Lin28 has important implications for our mechanistic understanding of pluripotency, the timing of development, and oncogenesis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom