Open AccessThe Dangers of Transcription
Author(s) -
Stephan Mathas,
Tom Misteli
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.11.037
Subject(s) - chromosomal translocation , biology , transcription (linguistics) , genetics , genome , transcription factor , microbiology and biotechnology , gene , philosophy , linguistics
Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.
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