Pushing and Pulling: Microtubules Mediate Meiotic Pairing and Synapsis
Author(s) -
Sue L. Jaspersen,
R. Scott Hawley
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.11.013
Subject(s) - synapsis , pairing , biology , meiosis , caenorhabditis elegans , homologous chromosome , microbiology and biotechnology , genetics , synaptonemal complex , microtubule , gene , physics , superconductivity , quantum mechanics
Meiotic pairing in the nematode Caenorhabditis elegans is facilitated by chromosomal sites known as pairing centers that are tethered to the nuclear envelope. Sato et al. (2009) and Penkner et al. (2009) provide insight into how proteins linking pairing centers and the microtubule cytoskeleton mediate homolog pairing and restrict synapsis to homologous pairs of chromosomes.
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