Open AccessHow to Drive Your Helicase in a Straight Line
Author(s) -
Anna Marie Pyle
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.10.016
Subject(s) - biology , helicase , line (geometry) , genetics , microbiology and biotechnology , gene , rna , geometry , mathematics
Helicases are molecular motors that move along and remodel DNA, RNA, and associated protein complexes. Helicases are often directional. By analyzing crystal structures in complexes with RNA and ATP analogs, Thomsen and Berger (2009) now elucidate the molecular basis for unidirectional motion by the hexameric RNA helicase Rho.
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