Open AccessTetherin Is as Tetherin Does
Author(s) -
J. Hammonds,
Paul Spearman
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.10.011
Subject(s) - tetherin , biology , microbiology and biotechnology , virology , viral envelope , human immunodeficiency virus (hiv) , cell , genetics
Tetherin is a cellular restriction factor that inhibits the release of HIV and other enveloped viruses from host cells. A paper from Perez-Caballero et al. (2009) in this issue of Cell clarifies how this factor works. The authors show that the aptly named tetherin directly tethers viral particles to the plasma membrane.
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