MAP-ping Unconventional Protein-DNA Interactions
Author(s) -
Elhadji M. Dioum,
Eric Wauson,
Melanie H. Cobb
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.10.007
Subject(s) - biology , chromatin immunoprecipitation , gene expression , gene , chromatin , regulation of gene expression , dna microarray , transcription factor , dna , transcription (linguistics) , computational biology , genetics , microbiology and biotechnology , promoter , linguistics , philosophy
Control of gene expression depends on a myriad of protein-DNA interactions, and the number of proteins involved just got larger. In this issue, Hu et al. (2009) identify hundreds of human proteins that bind to DNA, including many surprises such as the protein kinase ERK2 (MAPK1) that now appears to control gene expression directly.
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