Open AccessCondensin(g) Crossover Control to a Few Breaks
Author(s) -
Simon J. Boulton
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.09.016
Subject(s) - biology , crossover , condensin , control (management) , genetics , computational biology , evolutionary biology , gene , chromosome , computer science , chromosome segregation , artificial intelligence
Meiotic chromosome pairs must receive at least one crossover to ensure proper segregation at the first meiotic division. Mets and Meyer (2009) now present compelling evidence that the establishment of higher-order chromosome structure by a condensin complex regulates crossover recombination by controlling the distribution and frequency of meiotic double-strand breaks.
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