Enhanced SnapShot: Antibiotic Inhibition of Protein Synthesis II | Zendy

Daniel Sohmen | Zendy; Joerg Harms | Zendy; Frank Schlünzen | Zendy; Daniel N. Wilson | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Enhanced SnapShot: Antibiotic Inhibition of Protein Synthesis II

Author(s) -

Daniel Sohmen,

Joerg Harms,

Frank Schlünzen,

Daniel N. Wilson

Publication year - 2009

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2009.08.009

Subject(s) - ribosome , biology , protein biosynthesis , transfer rna , messenger rna , 50s , ribosomal rna , rna , protein subunit , 30s , translation (biology) , antibiotics , ribosome profiling , biochemistry , microbiology and biotechnology , gene

The translational apparatus is one of the major targets for antibiotics in the bacterial cell. Antibiotics predominantly interact with the functional centers of the ribosome, namely the messenger RNA (mRNA)-transfer RNA (tRNA) decoding region on the 30S subunit, the peptidyltransferase center on the 50S subunit, or the ribosomal exit tunnel through which the nascent polypeptide chain passes during translation. Protein synthesis can be divided into three phases: initiation, elongation, and termination/recycling.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research