Open AccessEffects of bark flour of Passiflora edulis on food intake, body weight and behavioral response of rats
Author(s) -
Dandara Antonia Felizardo de Figueiredo,
Liana C.M. Pordeus,
Luciano Leite Paulo,
Renan Marinho Braga,
Diogo Vilar da Fonsêca,
Bruno Sousa,
Maria J. Costa,
Maria Conceição Rodrigues Gonçalves,
Klébya Hellen Dantas de Oliveira
Publication year - 2016
Publication title -
revista brasileira de farmacognosia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 46
eISSN - 1981-528X
pISSN - 0102-695X
DOI - 10.1016/j.bjp.2016.02.010
Subject(s) - passiflora , bark (sound) , sedative , body weight , open field , weight gain , chemistry , zoology , medicine , botany , biology , pharmacology , ecology
Effects of treatment with the bark flour of Passiflora edulis Sims, Passifloraceae, were evaluated. Adult male Wistar rats were treated for 30 days (130mg/kg, p.o.) with the albedo flour, flavedo and full bark of P. edulis, corresponding to albedo associated with flavedo. Behavioral response observed after treatment with bark flour P. edulis showed sedative effects by the reduction of exploratory activity and increased duration of immobility in the open field test for the group of animals that received the albedo flour associated with the flavedo. Sedative effects were observed in the absence of motor incoordination or muscle relaxation. Food intake of experimental animals was not changed, but the weight gain was decreased both in animals that received only albedo flour, and in those who received the full bark flour. The full bark flour of Passiflora showed sedative effects, without anxiolytic effect detectable and muscle relaxation or motor incoordination, and reduces body weight gain