Open AccessDevelopment and characterization of evening primrose (Oenothera biennis) oil nanoemulsions
Author(s) -
Railane Ferreira Rodrigues,
Isabele Campos Costa,
Fernanda Borges de Almeida,
Rodrigo Alves Soares Cruz,
Adriana Maciel Ferreira,
Jessica C.E. Vilhena,
Alexandro Cezar Florentino,
J.C.T. Carvalho,
Caio P. Fernandes
Publication year - 2015
Publication title -
revista brasileira de farmacognosia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 46
eISSN - 1981-528X
pISSN - 0102-695X
DOI - 10.1016/j.bjp.2015.07.014
Subject(s) - evening primrose , oenothera , evening primrose oil , dispersity , onagraceae , botany , biology , chemistry , food science , organic chemistry
Evening primrose (Oenothera biennis L., Onagraceae) seeds oil has great economic importance due to its wide industrial application, mainly for medicines and nutraceutics. However, to our knowledge, it remains almost unexplored regarding development of innovative formulations, such as nanoemulsions. On the present study, required Hydroprophile–Lipophile Balance of evening primrose seeds oil was determined (HLB 12) and a stable nanoemulsion (Day 1: mean droplet size: 214.3±0.69nm, polydispersity index: 0.253±0.012. Day 7: mean droplet size: 202.8±0.23nm, polydispersity index: 0.231±0.008) was achieved. Moreover, pseudo-ternary diagram allowed delimitation of nanoemulsion region, contributing to nanobiotechnology of natural products