Open AccessEvaluation of larvicidal activity of a nanoemulsion of Rosmarinus officinalis essential oil
Author(s) -
Jonatas Lobato Duarte,
Jesús Rafael Rodríguez Amado,
Anna Eliza Maciel de Faria Mota Oliveira,
Rodrigo Alves Soares Cruz,
Adriana Maciel Ferreira,
Raimundo ato Picanço Souto,
Deborah Quintanilha Falcão,
José Carlos Tavares Carvalho,
Caio P. Fernandes
Publication year - 2015
Publication title -
revista brasileira de farmacognosia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 46
eISSN - 1981-528X
pISSN - 0102-695X
DOI - 10.1016/j.bjp.2015.02.010
Subject(s) - rosmarinus , officinalis , aedes aegypti , essential oil , context (archaeology) , dispersity , traditional medicine , lamiaceae , biology , chemistry , food science , larva , botany , medicine , organic chemistry , paleontology
Nanotechnology has emerged as a promising area for innovative products, including insecticides. Dengue is a tropical disease which is considered a critical health problem in developing countries, due to negative impacts to the environment caused by synthetic chemicals used for vector control (Aedes aegypti). Thus, developing of natural products based insecticidal are considered very promising. On this context, the aim of the present study was to obtain an O/W nanoemulsion containing Rosmarinus officinalis L., Lamiaceae, essential oil and evaluate its larvicidal activity against A. aegypti. Low energy method was employed, allowing achievement of small droplets. The nanoemulsion also presented low polydispersity and mean droplet below 200 nm, even after 30 days of storage. Potential mortality levels were observed after 24 h (80 ± 10%) and 48 h (90 ± 10%) in A. aegypti larvae at final concentration of 250 ppm, related to R. officinalis essential oil. This study contributes to nanobiotechnology of natural products, presenting a potential larvicidal nanoemulsion prepared with R. officinalis essential oil. Moreover, nanoemulsion production involved a non-heating procedure, describing easy technique which may be useful for integrative control programs