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Prospective evaluation of clarithromycin in recurrent chronic rhinosinusitis with nasal polyps
Author(s) -
Thiago Freire Pinto Bezerra,
Rogério Pezato,
Pâmella Marletti de Barros,
Larissa Leal Coutinho,
Leidianny Firmino Costa,
Fábio Pinna,
Richard Louis Voegels
Publication year - 2019
Publication title -
brazilian journal of otorhinolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.488
H-Index - 33
eISSN - 1808-8694
pISSN - 1808-8686
DOI - 10.1016/j.bjorl.2019.09.008
Subject(s) - medicine , clarithromycin , nasal polyps , sinusitis , gastroenterology , interquartile range , prospective cohort study , nose , asthma , population , surgery , helicobacter pylori , environmental health
The antiinflammatory effects of macrolides, especially clarithromycin, have been described in patients with chronic rhinosinusitis without polyps and also other chronic inflammatory airway diseases. There is no consensus in the literature regarding the effectiveness of clarithromycin in patients with chronic rhinosinusitis with sinonasal polyposis and the national literature does not report any prospective studies on the efficacy of clarithromycin in chronic rhinosinusitis in our population.

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