Open AccessReverse effect of curcumin on CDDP-induced drug-resistance via Keap1/p62-Nrf2 signaling in A549/CDDP cell
Author(s) -
Jie Shen,
Yajuan Chen,
Yuanwei Jia,
Wenying Zhao,
Guanghai Chen,
DingFeng Liu,
Yunyu Chen,
Chao Zhang,
Xiaoping Liu
Publication year - 2017
Publication title -
asian pacific journal of tropical medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.491
H-Index - 52
ISSN - 1995-7645
DOI - 10.1016/j.apjtm.2017.10.028
Subject(s) - curcumin , autophagy , keap1 , a549 cell , chemistry , apoptosis , cell , programmed cell death , microbiology and biotechnology , transcription factor , pharmacology , cancer research , biology , biochemistry , gene
To assess the effect of curcumin on CDDP-induced drug resistance and explore the underlying molecular mechanism through Nrf2 system and autophagy pathway.
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