Antioxidants: Friend or foe? | Zendy

Rangaprasad Sarangarajan | Zendy; S. Meera | Zendy; Rukkumani Rajagopalan | Zendy; P. Sankar | Zendy; Anuradha K. Gajjar | Zendy

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Antioxidants: Friend or foe?

Author(s) -

Rangaprasad Sarangarajan,

S. Meera,

Rukkumani Rajagopalan,

P. Sankar,

Anuradha K. Gajjar

Publication year - 2017

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2017.10.017

Subject(s) - oxidative stress , disease , antioxidant , diabetes mellitus , cancer , medicine , reactive oxygen species , pharmacology , chemistry , biochemistry , endocrinology

Reactive oxygen species are the intermediates that are formed during the normal metabolic process which are effectively neutralized by the antioxidant system of the body. Any imbalance in this neutralization process causes oxidative stress which has been implicated as one of the cause in diseases such as Alzheimer's disease, cardiovascular disorders, cancer etc. Research has enabled the use of antioxidants as therapeutic agents in the treatment of various diseases. Literature also puts forth the negative effects of using antioxidants in the treatment of diseases. This review is a compilation of both the beneficial and detrimental effects of use of antioxidants in the treatment of diseases such as cancer, cardiovascular diseases, diabetes and oral diseases.

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