Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in vitro | Zendy

Jiangzheng Zeng | Zendy; Yu Liu | Zendy; Fen Huang | Zendy; He Zhihui | Zendy; Huamao Sun | Zendy; Yanda Lu | Zendy; Junhua Lei | Zendy; Rongcheng Luo | Zendy

Open Access

Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in vitro

Author(s) -

Jiangzheng Zeng,

Yu Liu,

Fen Huang,

He Zhihui,

Huamao Sun,

Yanda Lu,

Junhua Lei,

Rongcheng Luo

Publication year - 2017

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2017.10.013

Subject(s) - glypican 3 , cytotoxic t cell , epitope , peptide , cytotoxicity , antigen , peptide vaccine , biology , in vitro , microbiology and biotechnology , immunotherapy , antibody , human leukocyte antigen , immunology , chemistry , immune system , cancer research , hepatocellular carcinoma , biochemistry

To investigate potential human leucocyte antigen (HLA)-A2-restricted epitope peptides of glypican-3 (GPC3) and determine the cytotoxicity of peptide-specific cytotoxic T lymphocytes (CTLs) against hepatocellular carcinoma (HCC) cells.

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