In vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype | Zendy

Imran Shahid | Zendy; Waleed Hassan Almalki | Zendy; Mohammed W. Al-Rabia | Zendy; Mohammed Hasan Mukhtar | Zendy; Shaia Almalki | Zendy; Saad A. Alkahtani | Zendy; Sami S. Ashgar | Zendy; Hani Faidah | Zendy; Muhammad Hassan Hafeez | Zendy

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In vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype

Author(s) -

Imran Shahid,

Waleed Hassan Almalki,

Mohammed W. Al-Rabia,

Mohammed Hasan Mukhtar,

Shaia Almalki,

Saad A. Alkahtani,

Sami S. Ashgar,

Hani Faidah,

Muhammad Hassan Hafeez

Publication year - 2017

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2017.07.011

Subject(s) - microbiology and biotechnology , transfection , small interfering rna , biology , ns3 , mtt assay , viral replication , cell culture , virology , cell growth , blot , cell , virus , clone (java method) , rna interference , gene expression , hepatitis c virus , gene , rna , biochemistry , genetics

To explore inhibitory effects of genome-specific, chemically synthesized siRNAs (small interference RNA) against NS3 gene of hepatitis C virus (HCV) 1a genotype in stable Huh-7 (human hepatoma) cells as well as against viral replication in serum-inoculated Huh-7 cells.

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