Atractylenolide Ⅰ protects against lipopolysaccharide-induced disseminated intravascular coagulation by anti-inflammatory and anticoagulation effect | Zendy

Xiaomei Tang | Zendy; Zhi-Kai Liao | Zendy; Youwei Huang | Zendy; Xi Lin | Zendy; LiangCai Wu | Zendy

Open Access

Atractylenolide Ⅰ protects against lipopolysaccharide-induced disseminated intravascular coagulation by anti-inflammatory and anticoagulation effect

Author(s) -

Xiaomei Tang,

Zhi-Kai Liao,

Youwei Huang,

Xi Lin,

LiangCai Wu

Publication year - 2017

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2017.06.007

Subject(s) - lipopolysaccharide , pharmacology , tumor necrosis factor alpha , disseminated intravascular coagulation , western blot , in vivo , medicine , coagulation , chemistry , immunology , biology , biochemistry , microbiology and biotechnology , gene

To investigate whether atractylenolide Ⅰ (ATL-Ⅰ) has protective effect on lipopolysaccharide (LPS)-induced disseminated intravascular coagulation (DIC) in vivo and in vitro, and explore whether NF-κB signaling pathway is involved in ATL-Ⅰ treatment.

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