Preoperative application of combination of portal venous injection of donor spleen cells and intraperitoneal injection of rapamycin prolongs the survival of cardiac allografts in mice | Zendy

Wenlin Gong | Zendy; Chuang Sha | Zendy; Gang Du | Zendy; Zhonggui Shan | Zendy; Zhongquan Qi | Zendy; Sufang Zhou | Zendy; Nuo Yang | Zendy; Yongxiang Zhao | Zendy

Open Access

Preoperative application of combination of portal venous injection of donor spleen cells and intraperitoneal injection of rapamycin prolongs the survival of cardiac allografts in mice

Author(s) -

Wenlin Gong,

Chuang Sha,

Gang Du,

Zhonggui Shan,

Zhongquan Qi,

Sufang Zhou,

Nuo Yang,

Yongxiang Zhao

Publication year - 2017

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2017.05.004

Subject(s) - foxp3 , medicine , spleen , intraperitoneal injection , sirolimus , transplantation , immune system , heart transplantation , il 2 receptor , pharmacology , immunology , t cell

To investigate the effects of preoperative portal venous injection of donor spleen cells (PVIDSC) and intraperitoneal injection of rapamycin in the acute rejection of cardiac allograft in mice and the underlying mechanisms.

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