Seronegative disseminated Bartonella spp. infection in an immunocompromised patient | Zendy

Claudia Weilg | Zendy; Olguita del Águila | Zendy; Fernando Mazulis | Zendy; Wilmer Silva-Caso | Zendy; Carlos Alva-Urcia | Zendy; Rosario Cerpa-Polar | Zendy; Erick Mattos-Villena | Zendy; Juana del Valle-Mendoza | Zendy

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Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

Author(s) -

Claudia Weilg,

Olguita del Águila,

Fernando Mazulis,

Wilmer Silva-Caso,

Carlos Alva-Urcia,

Rosario Cerpa-Polar,

Erick Mattos-Villena,

Juana del Valle-Mendoza

Publication year - 2016

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2016.11.001

Subject(s) - bartonella henselae , serology , bartonella , cat scratch disease , medicine , polymerase chain reaction , bartonellosis , virology , immunology , pathology , biology , antibody , disease , gene , biochemistry

An 11 year old, hispanic girl with a history of B-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with Bartonella henselae infection. The first molecularly diagnosed case of disseminated Bartonella henselae infection was reported in an immunocompromised patient in Lima, Peru. The analysis was confirmed by Polymerase Chain Reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient's past exposures with cats should also be elicited.

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