Evaluation of hypoxia inducible factor targeting pharmacological drugs as antileishmanial agents | Zendy

Marina Dal'Bó Pelegrini | Zendy; Juliana Biar Pereira | Zendy; Solange dos Santos Costa | Zendy; Myriam Janeth Salazar Terreros | Zendy; Adriana Degrossoli | Zendy; Selma Giorgio | Zendy

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Evaluation of hypoxia inducible factor targeting pharmacological drugs as antileishmanial agents

Author(s) -

Marina Dal'Bó Pelegrini,

Juliana Biar Pereira,

Solange dos Santos Costa,

Myriam Janeth Salazar Terreros,

Adriana Degrossoli,

Selma Giorgio

Publication year - 2016

Publication title -

asian pacific journal of tropical medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.491

H-Index - 52

ISSN - 1995-7645

DOI - 10.1016/j.apjtm.2016.05.018

Subject(s) - resveratrol , pharmacology , ic50 , in vivo , mimosine , parasite load , chemistry , hypoxia inducible factors , viability assay , in vitro , biology , immunology , biochemistry , immune system , microbiology and biotechnology , botany , gene , leucaena leucocephala

To evaluate whether hypoxia inducible factor (HIF-1α) targeting pharmacological drugs, echinomycin, resveratrol and CdCl2 which inhibit HIF-1α stimulation, and mimosine, which enhances the stability of HIF-1α present antileishmanial properties.

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