Open AccessProtective effect of apoptosis signal-regulating kinase 1 inhibitor against mice liver injury
Author(s) -
Ping He,
Bo Zeng,
Xiaoli Zhang,
Dianliang Fang,
Xia-Qia Zhou,
Ke-Qiang Wan,
Wenguang Tian
Publication year - 2016
Publication title -
asian pacific journal of tropical medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.491
H-Index - 52
ISSN - 1995-7645
DOI - 10.1016/j.apjtm.2016.01.029
Subject(s) - acetaminophen , glutathione , apoptosis , liver injury , kinase , chemistry , malondialdehyde , medicine , pharmacology , endocrinology , hepatocyte , oxidative stress , enzyme , biochemistry , in vitro
To explore the protective effect and its molecular mechanism of apoptosis signal-regulating kinase 1 (ASK1) inhibitor (GS-459679) on acetaminophen-induced liver injury in mice.
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