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Effect of propofol on generation of inflammatory mediator of monocytes
Author(s) -
Yun Nie,
Yan-Xi Lu,
Lihong Lv
Publication year - 2015
Publication title -
asian pacific journal of tropical medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.491
H-Index - 52
ISSN - 1995-7645
DOI - 10.1016/j.apjtm.2015.10.008
Subject(s) - lipopolysaccharide , tumor necrosis factor alpha , secretion , propofol , stimulation , peripheral blood mononuclear cell , monocyte , pharmacology , thp1 cell line , receptor , chemistry , medicine , cell culture , endocrinology , biology , biochemistry , in vitro , genetics
To evaluate the effect of propofol with different concentrations on the expression of inflammatory mediators of interleukin and tumor-necrosis factor-α (TNF-α) by stimulating the mouse primary monocytes and human monocytic cell line with lipopolysaccharide (LPS) and also discuss the effect of propofol on the secretion of inflammatory mediator and its possible molecular mechanism.

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