Diet-induced obesity alters kinematics of rat spermatozoa | Zendy

Ibukun P. Oyeyipo | Zendy; Pieter Johann Maartens | Zendy; Stefan S. du Plessis | Zendy

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Diet-induced obesity alters kinematics of rat spermatozoa

Author(s) -

Ibukun P. Oyeyipo,

Pieter Johann Maartens,

Stefan S. du Plessis

Publication year - 2015

Publication title -

asian pacific journal of reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.167

H-Index - 17

eISSN - 2305-0519

pISSN - 2305-0500

DOI - 10.1016/j.apjr.2015.06.008

Subject(s) - sperm , motility , andrology , sperm motility , endocrinology , staining , medicine , biology , chemistry , microbiology and biotechnology , genetics

Objective: To investigate the effect of DIO on the kinematics and viability of spermatozoa in an albino rat model.Methods: Sperm suspensions from normal (Control) and diet-induced obese (DIO) Wistar rats were collected and incubated for various times (30, 60, 120 or 180 min at 37 °C). Motility parameters were analyzed with computer-aided sperm analysis (CASA), while viability was assessed by means of a dye exclusion staining technique (eosin/nigrosin).Results: Results reveal that there was a significant time dependent decrease (P < 0.05) in progressive motility, curvilinear velocity and beat cross-frequency after 60 min, while amplitude of lateral head displacement and sperm viability was significantly reduced (P < 0.05) after 120 min in the DIO group compared to control spermatozoa.Conclusions: These results provided evidence that obesity is detrimental to sperm parameter in rats possibly through increased testicular temperature as a result of a rise in fat deposition

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