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Perioperative Pharmacology: Blood Coagulation Modifiers
Author(s) -
Hicks Rodney W.,
Wanzer Linda J.,
Goeckner BradLee
Publication year - 2011
Publication title -
aorn journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.222
H-Index - 43
eISSN - 1878-0369
pISSN - 0001-2092
DOI - 10.1016/j.aorn.2011.01.012
Subject(s) - perioperative , medicine , antithrombotic , partial thromboplastin time , coagulation , intensive care medicine , prothrombin time , perioperative nursing , heparin , coagulation disorder , thromboplastin , anesthesia , surgery
Blood coagulation is the process that results in the formation of a blood clot to stop bleeding from a damaged blood vessel. Various pharmacologic agents can affect the coagulation process. The American College of Chest Physicians' evidence‐based practice guidelines for perioperative management of antithrombotic therapy provide guidance for anticoagulant or antiplatelet therapy and bridge therapy. Perioperative nurses must understand the pharmacologic principles of the most common blood coagulation modifiers related to perioperative use. The perioperative nurse's responsibilities regarding administration of blood coagulation modifiers include reviewing the patient's pertinent laboratory results (eg, prothrombin time, partial thromboplastin time, international normalized ratio), recognizing the underlying conditions that require blood coagulation therapy, and documenting all pertinent information. Perioperative nurses also should participate in development of detailed storage and retrieval policies related to heparin.