Open AccessArtificial gut and the applications in poultry: A review
Author(s) -
Nishchal K. Sharma,
Shubiao Wu,
Natalie K. Morgan,
Tamsyn M. Crowley
Publication year - 2022
Publication title -
animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 28
eISSN - 2405-6545
pISSN - 2405-6383
DOI - 10.1016/j.aninu.2021.12.010
Subject(s) - gut microbiome , biology , gut flora , microbiology and biotechnology , microbiome , biochemical engineering , bioinformatics , engineering , biochemistry
Artificial gut models including both the gastric and intestinal phases have been used in poultry research for decades to predict the digestibility of nutrients, the efficacy of feed enzymes and additives, and caecal fermentation. However, the models used in the past are static and cannot be used to predict interactions between the feed, gut environment and microbiome. It is imperative that a standard artificial gut model for poultry is established, to enable these interactions to be examined without continual reliance on animals. To ensure the validity of an artificial model, it should be validated with in vivo studies. This review describes current practices in the use of artificial guts in research, their importance in poultry nutrition studies and highlights an opportunity to develop a dynamic gut model for poultry to reduce the number of in vivo experiments.