Open AccessReactive oxygen and nitrogen species regulate porcine embryo development during pre-implantation period: A mini-review
Author(s) -
Zhen Luo,
Jianbo Yao,
Jianxiong Xu
Publication year - 2021
Publication title -
animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 28
eISSN - 2405-6545
pISSN - 2405-6383
DOI - 10.1016/j.aninu.2021.03.007
Subject(s) - conceptus , embryo , biology , andrology , embryogenesis , microbiology and biotechnology , uterus , endometrium , in utero , reactive oxygen species , pregnancy , intracellular , period (music) , elongation , fetus , endocrinology , genetics , medicine , physics , materials science , ultimate tensile strength , acoustics , metallurgy
Significant porcine embryonic loss occurs during conceptus morphological elongation and attachment from d 10 to 20 of pregnancy, which directly decreases the reproductive efciency of sows. A successful establishment of pregnancy mainly depends on the endometrium receptivity, embryo quality, and utero-placental microenvironment, which requires complex cross-talk between the conceptus and uterus. The understanding of the molecular mechanism regulating the uterine-conceptus communication during porcine conceptus elongation and attachment has developed in the past decades. Reactive oxygen and nitrogen species, which are intracellular reactive metabolites that regulate cell fate decisions and alter their biological functions, have recently reportedly been involved in porcine conceptus elongation and attachment. This mini-review will mainly focus on the recent researches about the role of reactive oxygen and nitrogen species in regulating porcine embryo development during the pre-implantation period.