Open AccessInsights into host-microbe interaction: What can we do for the swine industry?
Author(s) -
Lijuan Fan,
Bingnan Liu,
ZiYi Han,
Wenkai Ren
Publication year - 2021
Publication title -
animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 28
eISSN - 2405-6545
pISSN - 2405-6383
DOI - 10.1016/j.aninu.2020.10.003
Subject(s) - biology , host (biology) , microbiome , gut–brain axis , gut flora , gut microbiome , function (biology) , brain function , colonization , microbiology and biotechnology , ecology , bioinformatics , biochemistry , evolutionary biology , neuroscience
Recent discoveries have underscored the cross-talk between intestinal microbes and their hosts. Notably, intestinal microbiota impacts the development, physiological function and social behavior of hosts. This influence usually revolves around the microbiota-gut-brain axis (MGBA). In this review, we firstly outline the impacts of the host on colonization of intestinal microorganisms, and then highlight the influence of intestinal microbiota on hosts focusing on short-chain fatty acid (SCFA) and tryptophan metabolite-mediated MGBA. We also discuss the intervention of intestinal microbial metabolism by dietary supplements, which may provide new strategies for improving the welfare and production of pigs. Overall, we summarize a state-of-the-art theory that gut microbiome affects brain functions via metabolites from dietary macronutrients.