Open AccessIncreased Expression and Activity of Phospholipase C in Renal Arterioles of Young Spontaneously Hypertensive Rats
Author(s) -
Z PENG,
Anna Dang,
William J. Arendshorst
Publication year - 2006
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2006.06.009
Subject(s) - medicine , endocrinology , kidney , blood pressure
The aims of this study were to document the presence of phospholipase C (PLC) isozymes beta(1), gamma(1), and delta(1) in freshly isolated renal glomeruli and resistance vessels, to compare their expression and activity to that in aorta, and to contrast values between 6-week-old Wistar-Kyoto (WKY) controls and 6-week-old spontaneously hypertensive rats (SHR) during the developmental phase of genetic hypertension.
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