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Increased sputum levels of thymus and activation-regulated chemokine in children with asthma not eosinophilic bronchitis
Author(s) -
Min Jung Kim,
Hyung Soon Lee,
In Suk Sol,
Mi Na Kim,
Jung Yeon Hong,
Kyung Eun Lee,
Yoon Hee Kim,
Kyung Won Kim,
Myung Hyun Sohn,
K.-E. Kim
Publication year - 2017
Publication title -
allergologia et immunopathologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 37
eISSN - 1578-1267
pISSN - 0301-0546
DOI - 10.1016/j.aller.2016.12.004
Subject(s) - medicine , sputum , exhaled nitric oxide , asthma , eosinophil , eosinophilia , immunology , atopy , bronchial hyperresponsiveness , methacholine , spirometry , lung , respiratory disease , pathology , tuberculosis
Thymus and activation-regulated chemokine (TARC), a member of the CC chemokine family, plays a crucial role in Th2-specific inflammation. We aimed to determine the concentration of sputum TARC in children with asthma and eosinophilic bronchitis (EB) and its relation with eosinophilic inflammation, pulmonary function, and bronchial hyper-responsiveness.

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