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Amebic and cytomegalovirus colitis mimic ulcerative colitis
Author(s) -
Weng MengTzu,
Wei ShuChen,
Leong YewLoong,
Tung ChienChih,
Shun ChiaTung,
Wong JauMin
Publication year - 2016
Publication title -
advances in digestive medicine
Language(s) - English
Resource type - Journals
ISSN - 2351-9800
DOI - 10.1016/j.aidm.2014.10.002
Subject(s) - medicine , bloody diarrhea , ulcerative colitis , gastroenterology , colonoscopy , colitis , hypoalbuminemia , sulfasalazine , sepsis , nephrotic syndrome , mesalazine , abdominal pain , toxic megacolon , perforation , surgery , materials science , colorectal cancer , disease , cancer , punching , metallurgy
Summary Here we present a 50‐year‐old man who suffered from progressively bloody diarrhea for 2 months. A colonoscopy revealed pancolonic mucosal inflammation, ulceration, and spontaneous bleeding. Ulcerative colitis was initially diagnosed and sulfasalazine was prescribed. Hypoalbuminemia and renal function deterioration developed 1 year later. Steroids were prescribed for suspected nephrotic syndrome. His bloody diarrhea and abdominal symptoms worsened after steroid use. Progressive sepsis and acute renal function deterioration also developed. Positive human immunodeficiency virus (HIV) antibody was found during routine hemodialysis screening. An episode of colon perforation occurred and surgery was performed. The resected colon showed amoeba, cytomegalovirus, and fungal infection. The patient died of sepsis. In this report, we discuss how to diagnose ulcerative colitis. It is important to exclude infection before using an immunosuppressive agent.

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