Open AccessAlvimopan for post-operative ileus: What we should know?
Author(s) -
Abhijit Nair
Publication year - 2016
Publication title -
acta anaesthesiologica taiwanica
Language(s) - English
Resource type - Journals
eISSN - 1875-4597
pISSN - 1875-452X
DOI - 10.1016/j.aat.2016.10.001
Subject(s) - medicine , ileus , intestinal motility , drug , anesthesia , surgery , pharmacology , motility , genetics , biology
Alvimopan is an US-FDA approved, peripherally acting mu opioid receptor antagonist which when started pre-operatively has been shown to hasten intestinal motility and reduce the duration of post-operative ileus. However the logistics involved in procuring, storing and dispensing the drug and the cost of the drug for fifteen doses as approved by FDA prohibits the use of it on a regular basis.
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