Open AccessCepharanthine alleviates liver injury in a rodent model of limb ischemia–reperfusion
Author(s) -
Yin-Kuang Chang,
Su-Cheng Huang,
Ming-Chang Kao,
ChunJen Huang
Publication year - 2015
Publication title -
acta anaesthesiologica taiwanica
Language(s) - English
Resource type - Journals
eISSN - 1875-4597
pISSN - 1875-452X
DOI - 10.1016/j.aat.2015.11.004
Subject(s) - medicine , malondialdehyde , reperfusion injury , inflammation , nitric oxide , liver injury , hindlimb , ischemia , pharmacology , prostaglandin e2 , endocrinology , sham surgery , anesthesia , oxidative stress , pathology , alternative medicine
Limb ischemia-reperfusion (I/R) causes remote organ injury (e.g., liver injury). Oxidation and inflammation are crucial mechanisms. We investigated the effects of cepharanthine, a potent antioxidative and anti-inflammatory drug, on alleviating liver injury induced by limb I/R.
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