Thalamus and pain | Zendy

ChenTung Yen | Zendy; Pen-Li Lu | Zendy

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Thalamus and pain

Author(s) -

ChenTung Yen,

Pen-Li Lu

Publication year - 2013

Publication title -

acta anaesthesiologica taiwanica

Language(s) - English

Resource type - Journals

eISSN - 1875-4597

pISSN - 1875-452X

DOI - 10.1016/j.aat.2013.06.011

Subject(s) - thalamus , medicine , chronic pain , neuroscience , nociception , cortex (anatomy) , thalamic stimulator , consciousness , cerebral cortex , deep brain stimulation , psychology , physical therapy , disease , receptor , parkinson's disease

The thalamus is a key relay station for the transmission of nociceptive information to the cerebral cortex. We review the input-output connection, functional imaging, direct neuronal recording, stimulation, and lesioning studies on the involvement of thalamus in acute and chronic pain functions. Based on its specific reciprocal connection with the cerebral cortex, strong nociceptive responsiveness, and the severe chronic pain when it is damaged, the thalamus may hold the key to pain consciousness and the key to understanding spontaneous and evoked pain in chronic pain conditions. A work plan is proposed for future study.

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