Analgesic efficacy of tramadol/acetaminophen and propoxyphene/acetaminophen for relief of postoperative wound pain | Zendy

F.-S. Lin | Zendy; WenYing Lin | Zendy; Chia-Hsin Lai | Zendy; ChienYu Chen | Zendy; ChihPeng Lin | Zendy; Tzu-Fu Lin | Zendy; WeiZen Sun | Zendy

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Analgesic efficacy of tramadol/acetaminophen and propoxyphene/acetaminophen for relief of postoperative wound pain

Author(s) -

F.-S. Lin,

WenYing Lin,

Chia-Hsin Lai,

ChienYu Chen,

ChihPeng Lin,

Tzu-Fu Lin,

WeiZen Sun

Publication year - 2012

Publication title -

acta anaesthesiologica taiwanica

Language(s) - English

Resource type - Journals

eISSN - 1875-4597

pISSN - 1875-452X

DOI - 10.1016/j.aat.2012.05.009

Subject(s) - medicine , tramadol , acetaminophen , propoxyphene , analgesic , anesthesia , adverse effect , visual analogue scale , randomized controlled trial , opioid , surgery , receptor

Weak opioid combined with acetaminophen (APAP) has been proven to provide better analgesic efficacy and cause fewer complications than either drug alone. However, there are questions about whether different opioids, tramadol and propoxyphene, provide similar efficacy or safety. Thus, we investigated Ultracet (37.5 mg tramadol/325 mg APAP) and Depain-X (65 mg propoxyphene/650 mg APAP). The primary aims of this study were to compare the analgesic efficacy and adverse effects of single-dose oral Ultracet versus Depain-X in acute postoperative pain.

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