Open AccessAntinociceptive effects of combination of Tramadol and Acetaminophen on painful diabetic neuropathy in streptozotocin-induced diabetic rats†
Author(s) -
Yahong Gong,
Xuerong Yu,
Huili Liu,
Nan Yang,
Pingping Zuo,
Yuguang Huang
Publication year - 2011
Publication title -
acta anaesthesiologica taiwanica
Language(s) - English
Resource type - Journals
eISSN - 1875-4597
pISSN - 1875-452X
DOI - 10.1016/j.aat.2011.01.003
Subject(s) - medicine , nociception , tramadol , streptozotocin , tail flick test , hyperalgesia , diabetic neuropathy , acetaminophen , hot plate test , diabetes mellitus , pharmacology , anesthesia , analgesic , endocrinology , receptor
The purpose of this study was to establish the streptozotocin (STZ)-induced diabetic model with rats and investigate the antinociceptive effect of combination of Tramadol (TR) and Acetaminophen (NAPA) on the animal model for the first time.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom