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24 Trophic interactions in development of neural progenitors
Author(s) -
Kalcheim Chava
Publication year - 1996
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(96)80219-x
Subject(s) - citation , trophic level , computer science , library science , biology , ecology
Neural crest ceIIs give rise to neuronal and non-neuronal derivatives in precise locations in vertebrate embryos. Crest-derived neuogenic precursors appear to disperse and differentiate only on a medial migration pathway leading into somitic sclerotome. whereas melanocyte precursors disperse on a lateral migration pathway between the dermamyotome and overlying cctodemlal epithelium. Evidence will be presented that developmentallydistinct subpopulations arise in the premigratory newal crest cell population (Weston, Henion), that these cells respond differentially to environmentaJ cues localized on the crest migration pathways (Henion, Kalcheim), and that growth-factor mediated changes in the s!nxture of the embryonic environment regulate the onsct of dispersal of crest-derived subpopulations (Tosney, Kalcheim).