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DNA neosynthesis in Auerbach plexus ganglia isolated from the rat hypertrophic gut: An electrophoretic analysis
Author(s) -
Robecchi Maria G. Giacobini,
Borrione Paolo,
Canavese Marco,
Guena Stefano,
Paraninfo Adriana,
Poncino Alessandro,
Silengo Lorenzo
Publication year - 1995
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(95)00035-f
Subject(s) - myenteric plexus , dna , biology , genomic dna , plexus , electrophoresis , microbiology and biotechnology , anatomy , pathology , genetics , immunohistochemistry , medicine , immunology
We analysed using electrophoresis the total genomic DNA extracted from isolated Auerbach plexus ganglia of the hypertrophic duodenum upstream from a partial experimental stenosis. Results indicated the presence of two extra‐bands migrating below the high molecular weight DNA, suggesting that DNA amplification is the basic mechanism of the DNA neosynthesis previously observed in myenteric neurons.