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Nuclear patterns of apoptotic and developing neurons of superior cervical ganglion of newborn rat
Author(s) -
Diana Andrea,
Setzu Mariella,
Sirigu Silvia,
Diaz∗ Giacomo
Publication year - 1993
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(93)90066-m
Subject(s) - superior cervical ganglion , biology , involution (esoterism) , apoptosis , programmed cell death , neuroscience , neuron , chromatin , cervical ganglia , ganglion , degeneration (medical) , anatomy , pathology , medicine , genetics , dna , consciousness
Superior cervical ganglion (SCG) neurons of female rats aged 3, 5 and 7 days revealed conspicuous nuclear changes in neurons undergoing postnatal cell death. Several qualitative and quantitative data such as nuclear size and shape, the presence of atypical chromocenters and chromatin textural features discriminated well neurons candidate to degeneration and those advancing in the direction of adult maturation. At least on morphological grounds, postnatal death of SCG neurons appears to be of apoptotic type. The sequence of nuclear events observed enables the recognition of the early stages of involution which prelude neuron degeneration.