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Developing rat cerebellum—III Effects of abnormal thyroid states and undernutrition on gangliosides
Author(s) -
Vitiello F.,
Clos J.,
Di Benedetta C.,
Gombos G.
Publication year - 1989
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(89)90055-5
Subject(s) - ganglioside , cerebellum , thyroid , endocrinology , malnutrition , medicine , cell , biology , chemistry , biochemistry
Alteration of rat postnatal cerebellar development produced by undernutrition, thyroxine treatment and thyroid deficiency also involves ganglioside deposition. The distribution of the different ganglioside types is apparently unaffected but quantitative alterations are present that reflect the reduction of cell number and cell process surface in the adult, and either acceleration or slowing down or reduction of cell formation and maturation occurring during cerebellar development in the three experimental situations.